MRT 68921 dihydrochloride
Cat. No. 5780
Chemical Name: N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-te
Biological ActivityPotent ULK inhibitor (IC50 values are 1.1 and 2.9 nM for ULK2 and ULK1, respectively). Inhibits autophagy in mouse embryonic fibroblasts.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Petherick et al (2015) Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J.Biol.Chem. 290 11376. PMID: 25833948.
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Keywords: MRT 68921 dihydrochloride, supplier, MRT68921, dihydrochloride, ULK1, 2, inhibitors, inhibits, autophagy, potent, Tocris Bioscience, Other Kinase Inhibitor products
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