2-Phospho-L-ascorbic acid trisodium salt

Cat. No. 5778

2-Phospho-L-ascorbic acid trisodium salt C6H6Na3O9P [66170-10-3]

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Chemical Name: 2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt

Biological Activity

Stable ascorbic acid derivative used in cell culture; in combination with FGF-2, maintains differentiation potential in bone marrow-derived mesenchymal stem cells (MSC) through increased expression of HGF. Also exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine (Cat. No. 5619).

Technical Data

Soluble to 100 mM in water
>95 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Bae et al (2015) L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor. Growth Factors 33 71. PMID: 25714612.

Li et al (2015) Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis. Sci.Rep. 5 9819. PMID: 25909282.

Falcon et al (2014) An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors. PLoS One 9 e106901. PMID: 25210890.

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Keywords: 2-Phospho-L-ascorbic acid trisodium salt, supplier, Vitamin, C, L-Ascorbic, acid, derivative, stem, cells, culture, mesenchymal, cytoprotective, Tocris Bioscience, Mesenchymal Stem Cells products

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