Ac-IEPD-AFC

Cat. No. 1576

Ac-IEPD-AFC N-Ac-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin)

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Chemical Name: N-Acetyl-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin)

Biological Activity

Peptide sequence shown to be preferred recognition motif for the serine protease granzyme B. Fluorogenic substrate.

Technical Data

M.Wt:
725.67
Formula:
C32H38F3N5O11
Sequence:
IEPD

(Modifications: Ile-1 = N-Ac-Ile, Asp-4 = Asp-(7-amino-4-trifluoromethylcoumarin))

Solubility:
Soluble to 14.51 mg/ml in DMSO
Storage:
Desiccate at -20°C
CAS No:
1135417-31-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Data Sheet: View Safety Data Sheet

Thornberry et al (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B. J.Biol.Chem. 272 17907. PMID: 9218414.

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Keywords: Ac-IEPD-AFC, supplier, Fluorogenic, granzyme, B, Caspases, Proteinases, Proteases, Tocris Bioscience, Caspase Substrate products

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