Cat. No. 1575
Chemical Name: N-Acetyl-Leu-Glu-His-Asp-(7-amino-4
Biological ActivityFluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.
(Modifications: Leu-1 = N-Ac-Leu, Asp-4 = Asp-(7-amino-4-trifluoromethyl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Moriya et al (2000) Mechanism of nitric oxide-induced apoptosis in human neuroblastoma SH-SY5Y cells. FEBS Lett. 484 253. PMID: 11078888.
Ito et al (1999) Possible involvement of cytochrome c release and sequential activation of caspases in ceramide-induced apoptosis in SK-N-MC cells. Biochim.Biophys.Acta 1452 263. PMID: 10590315.
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Keywords: Ac-LEHD-AFC, supplier, Fluorogenic, caspases, Proteinases, Proteases, Tocris Bioscience, Caspase Substrate products
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