Cat. No. 5735
Chemical Name: 1-(3,4-Dimethylphenyl)-N,N-dipropyl
Biological ActivitySuppresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation (IC50 = 1.7 μM). Suppresses HIF-1α accumulation and enhances survival and function of primary pancreatic islets in vitro. Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Orr et al (2015) Suppressors of superoxide production from mitochondrial complex III. Nat.Chem.Biol. 11 834. PMID: 26368590.
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Keywords: S3QEL 2, supplier, S3QEL2, Suppresses, superoxide, production, complex, III, mitochondria, oxidative, phosphorylation, ROS, reactive, oxygen, species, inhibitors, inhibits, Tocris Bioscience, ROS and Other Gaseous Donor products
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