Cat. No. 5735
Chemical Name: 1-(3,4-Dimethylphenyl)-N,N-dipropyl
Biological ActivitySuppresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation (IC50 = 1.7 μM). Suppresses HIF-1α accumulation and enhances survival and function of primary pancreatic islets in vitro. Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Orr et al (2015) Suppressors of superoxide production from mitochondrial complex III. Nat.Chem.Biol. 11 834. PMID: 26368590.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses S3QEL 2 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: S3QEL 2, supplier, S3QEL2, Suppresses, superoxide, production, complex, III, mitochondria, oxidative, phosphorylation, ROS, reactive, oxygen, species, inhibitors, inhibits, Tocris Bioscience, ROS and Other Gaseous Donor products
Find multiple products by catalog number
October 30 - November 3, 2016
Boston, MA, USA