Ogerin

Cat. No. 5722

Ogerin C17H17N5O [1309198-71-7]

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Chemical Name: 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol

Biological Activity

Selective positive allosteric modulator at GPR68 (pEC50 = 6.83). Exhibits selectivity for GPR68 over 58 other GPCRs. Attenuates contextual-based fear memory in mice.

Technical Data

M.Wt:
307.35
Formula:
C17H17N5O
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
1309198-71-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Huang et al (2015) Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature 527 477. PMID: 26550826.

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Keywords: Ogerin, supplier, positive, allosteric, modulators, GPR68, selective, learning, memory, Tocris Bioscience, Orphan 7-TM Receptor Modulator products

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