Cat. No. 5722new

Ogerin C17H17N5O [1309198-71-7]

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Chemical Name: 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol

Biological Activity

Selective positive allosteric modulator at GPR68 (pEC50 = 6.83). Exhibits selectivity for GPR68 over 58 other GPCRs. Attenuates contextual-based fear memory in mice.

Technical Data

Soluble to 100 mM in DMSO and to 20 mM in ethanol
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Huang et al (2015) Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature 527 477. PMID: 26550826.

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Keywords: Ogerin, supplier, positive, allosteric, modulators, GPR68, selective, learning, memory, Tocris Bioscience, Orphan 7-TM Receptor Modulator products

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