SKF 82958 hydrobromide
Cat. No. 5719
Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-pheny
Biological ActivityD1 agonist. Increases renal blood flow in animal models and promotes contralateral rotation in rats with unilateral lesions of the substantia nigra. Also augments GABAB inhibitory post-synaptic potentials (ipsp) in ventral tegmental area in brain slices.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Cameron and Williams (1993) Dopamine D1 receptors facilitate transmitter release. Nature 366 344. PMID: 8247128.
Pfeiffer et al (1982) Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines. J.Med.Chem. 25 352. PMID: 7069713.
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