SKF 82958 hydrobromide

Cat. No. 5719new

SKF 82958 hydrobromide C19H20ClNO2.HBr [74115-01-8]

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Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-1H-3-benzazepine-7,8-diol hydrobromide

Biological Activity

D1 agonist. Increases renal blood flow in animal models and promotes contralateral rotation in rats with unilateral lesions of the substantia nigra. Also augments GABAB inhibitory post-synaptic potentials (ipsp) in ventral tegmental area in brain slices.

Technical Data

Soluble to 100 mM in DMSO and to 5 mM in water with gentle warming
>98 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Cameron and Williams (1993) Dopamine D1 receptors facilitate transmitter release. Nature 366 344. PMID: 8247128.

Pfeiffer et al (1982) Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines. J.Med.Chem. 25 352. PMID: 7069713.

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Keywords: SKF 82958 hydrobromide, supplier, SKF82958, hydrobromide, dopamine, D1, agonists, agonism, Tocris Bioscience, D1 and D5 Receptor Agonist products

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