SKF 82958 hydrobromide
Cat. No. 5719
Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-pheny
Biological ActivityD1 agonist. Increases renal blood flow in animal models and promotes contralateral rotation in rats with unilateral lesions of the substantia nigra. Also augments GABAB inhibitory post-synaptic potentials (ipsp) in ventral tegmental area in brain slices.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Cameron and Williams (1993) Dopamine D1 receptors facilitate transmitter release. Nature 366 344. PMID: 8247128.
Pfeiffer et al (1982) Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines. J.Med.Chem. 25 352. PMID: 7069713.
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