Cat. No. 5714
Chemical Name: (1R,2S)-rel-2-[3,5-Difluoro-2-(phen
Biological ActivityLSD1 inhibitor (IC50 = 990 nM; Ki = 610 nM). Exhibits selectivity for LSD1 over MAO-B and MAO-A (Ki values are 17 and 110 μM, respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Mimasu et al (2010) Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1. Biochemistry 49 6494. PMID: 20568732.
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Keywords: S 2101, supplier, S2101, LSD1, inhibitors, inhibits, histones, demethylases, KDM1, Tocris Bioscience, Histone Demethylase Inhibitor products
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August 20 - 24, 2017
Paris , France