S 2101

Cat. No. 5714

S 2101 C16H15F2NO.HCl [1239262-36-2]

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Chemical Name: (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride

Biological Activity

LSD1 inhibitor (IC50 = 990 nM; Ki = 610 nM). Exhibits selectivity for LSD1 over MAO-B and MAO-A (Ki values are 17 and 110 μM, respectively).

Technical Data

M.Wt:
311.75
Formula:
C16H15F2NO.HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
1239262-36-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Mimasu et al (2010) Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1. Biochemistry 49 6494. PMID: 20568732.

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Keywords: S 2101, supplier, S2101, LSD1, inhibitors, inhibits, histones, demethylases, KDM1, Tocris Bioscience, Histone Demethylase Inhibitor products

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