Cat. No. 5694
Chemical Name: 2,4,6-Trimethyl-N-[[3'-(methylsulfon
Biological ActivityPotent LXR antagonist (pIC50 = 7.5). Enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells. Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Solt et al (2012) LXR-mediated inhibition of CD4+ T helper cells. PLoS ONE 7 e46615. PMID: 23029557.
Zuercher et al (2010) Discovery of tertiary sulfonamides as potent liver X receptor antagonists. J.Med.Chem. 53 3412. PMID: 20345102.
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Keywords: GSK 2033, supplier, GSK2033, Potent, LXR, antagonists, liver, x, receptors, Tocris Bioscience, LXR-like Receptor Antagonist products
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