Naloxone 3-glucuronide carbonic acid salt
Cat. No. 5684
Chemical Name: (5α)-4,5-Epoxy-14-hydroxy-6-oxo-17-(
Biological ActivityNaloxone conjugate. Following oral administration induces delayed diarrhea, as well as milder and delayed withdrawal behavior and tail skin temperature (TST) response compared with naloxone in morphine-dependent rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Simpkins et al (1988) Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates. J.Pharmacol.Exp.Ther. 244 195. PMID: 3335997.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Naloxone 3-glucuronide carbonic acid salt from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Naloxone 3-glucuronide carbonic acid salt, supplier, constipation, opioids, diarrhea, narcotics, glucuronide, conjugates, TST, tail, skin, temperature, Tocris Bioscience, Miscellaneous Opioid products
Find multiple products by catalog number
New Products in this Area
Fluorescent opioid antagonist; fluorescent-derivative of naloxone (Cat. No. 0599)BMS 986187
Potent δ-opioid receptor positive allosteric modulator
April 1 - 5, 2017
Washington, D.C., USA