Naloxone 3-glucuronide carbonic acid salt

Cat. No. 5684

Naloxone 3-glucuronide carbonic acid salt C25H29NO10.H2CO3

Price and Availability

For Naloxone 3-glucuronide carbonic acid salt pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (5α)-4,5-Epoxy-14-hydroxy-6-oxo-17-(2-propenyl)morphinan-3-yl β-D-glucopyranosiduronic acid carbonic acid salt

Biological Activity

Naloxone conjugate. Following oral administration induces delayed diarrhea, as well as milder and delayed withdrawal behavior and tail skin temperature (TST) response compared with naloxone in morphine-dependent rats.

Technical Data

M.Wt:
565.52
Formula:
C25H29NO10.H2CO3
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Simpkins et al (1988) Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates. J.Pharmacol.Exp.Ther. 244 195. PMID: 3335997.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Naloxone 3-glucuronide carbonic acid salt from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Naloxone 3-glucuronide carbonic acid salt, supplier, constipation, opioids, diarrhea, narcotics, glucuronide, conjugates, TST, tail, skin, temperature, Tocris Bioscience, Miscellaneous Opioid products

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

Appetite Modulation

Written by S. Tucci et al

Peptides Involved in Appetite Modulation Scientific Review

Our Peptides Involved in Appetite Modulation review gives an overview of the peptides implicated in appetite regulation and energy homeostasis. View PDF today.

divider line

Peripheral Sensitization

Written by Grant D. Nicol and Michael R. Vasko

Pain Life Science Poster

Our Peripheral Sensitization poster gives a summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. Request copy or view PDF today.

divider line

Mechanisms of Addiction

Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

divider line

New Products in this Area

Naloxone fluorescein acetate

Fluorescent opioid antagonist; fluorescent-derivative of naloxone (Cat. No. 0599)

BMS 986187

Potent δ-opioid receptor positive allosteric modulator

Sign-up for new product e-alerts
divider line

Bio-Techne Events

One Day Symposium

Bio-Techne Symposium 2017

Epigenetic Regulation of Stem Cell Differentiation

March 1, 2017

Amsterdam, The Netherlands