Naloxone 3-glucuronide carbonic acid salt
Cat. No. 5684
Chemical Name: (5α)-4,5-Epoxy-14-hydroxy-6-oxo-17-(
Biological ActivityNaloxone conjugate. Following oral administration induces delayed diarrhea, as well as milder and delayed withdrawal behavior and tail skin temperature (TST) response compared with naloxone in morphine-dependent rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Simpkins et al (1988) Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates. J.Pharmacol.Exp.Ther. 244 195. PMID: 3335997.
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Keywords: Naloxone 3-glucuronide carbonic acid salt, supplier, constipation, opioids, diarrhea, narcotics, glucuronide, conjugates, TST, tail, skin, temperature, Tocris Bioscience, Miscellaneous Opioid products
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