IRAK1/4 Inhibitor I

Cat. No. 5665

IRAK1/4 Inhibitor I C20H21N5O4 [509093-47-4]

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Chemical Name: N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide

Biological Activity

IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).

Technical Data

M.Wt:
395.41
Formula:
C20H21N5O4
Solubility:
Soluble to 20 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
509093-47-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Powers et al (2006) Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg.Med.Chem.Lett. 16 2842. PMID: 16563752.

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Citations are publications that use Tocris products.

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Keywords: IRAK1/4 Inhibitor I, supplier, IRAK1/4, inhibitors, inhibits, I, interleukin-1, receptor, associated, kinase, Tocris Bioscience, IRAK Inhibitor products

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