Cat. No. 5664
Chemical Name: Ethyl 2-[(4-chlorophenyl)amino]-4-thiazol
Biological ActivityOct3/4 inducer; promotes Oct3/4 expression and stabilizes the Oct3/4 protein in HEK293 cells. Induces expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1. Induces 15-fold increase in Oct3/4 expression in human primary fibroblasts.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Cheng et al (2015) Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4. J.Med.Chem. 58 5742. PMID: 26143659.
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Keywords: O4I2, supplier, octamer, binding, transcription, factors, oct4, inducing, compound, 2, Oct3/4, inducers, pluripotent, stem, cells, induction, Tocris Bioscience, Reprogramming products
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