Cat. No. 5659
Biological ActivityKV4 channel blocker. Blocks A-type K+ current (ISA) in mouse cerebellar granule neurons. The accessory dipeptidyl peptidase-like proteins (DPP) 6 and 10 are required for blockade.
(Modifications: X = Glp, Disulfide bridge: 8-28,13-33,17-35)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Maffie et al (2013) Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K+ channels. J.Physiol. 591 2419. PMID: 23440961.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses AmmTX3 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: AmmTX3, supplier, potassium, K+, channels, blockers, voltage-gated, Kv4, A-type, currents, DPP6, DPP10, venoms, Tocris Bioscience, Voltage-gated Potassium (KV) Channel Blocker products
Find multiple products by catalog number
New Products in this Area
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.