Cat. No. 5648
Chemical Name: 2-[[4-[(7-Chloro-4-quinolinyl)amino
Biological ActivityAutophagy inhibitor. Inhibits growth and induces apoptosis of renal cancer cells in vitro. Also inhibits TLR9.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Lee et al (2015) Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS ONE 10 e0131464. PMID: 26134285.
Lamphier et al (2014) Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol.Pharmacol. 85 429. PMID: 24342772.
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Citations are publications that use Tocris products.
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Keywords: Hydroxychloroquine sulfate, supplier, TLR9, toll-like, receptors, inhibitors, autophagy, inhibits, cancer, Tocris Bioscience, Autophagy Inhibitor products