Cat. No. 5648
Chemical Name: 2-[[4-[(7-Chloro-4-quinolinyl)amino
Biological ActivityAutophagy inhibitor. Inhibits growth and induces apoptosis of renal cancer cells in vitro. Also inhibits TLR9.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Lee et al (2015) Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS ONE 10 e0131464. PMID: 26134285.
Lamphier et al (2014) Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol.Pharmacol. 85 429. PMID: 24342772.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Hydroxychloroquine sulfate from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Hydroxychloroquine sulfate, supplier, TLR9, toll-like, receptors, inhibitors, autophagy, inhibits, cancer, Tocris Bioscience, Autophagy Inhibitor products
Find multiple products by catalog number
New Products in this Area
PCNA inhibitorPladienolide B
mRNA splicing inhibitor; antitumorLin28 1632
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.