O4I1

Cat. No. 5639

O4I1 C16H15NO2 [175135-47-4]

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Chemical Name: 4-[(4-Methoxyphenyl)methoxy]benzeneacetonitrile

Biological Activity

Oct3/4 inducer. Increases Oct3/4 mRNA levels in HEK293 cells by 2.5- and 4-fold at 10 μM and 20 μM, respectively. Also increases expression of Oct3/4 in human adult and neonatal fibroblasts.

Technical Data

M.Wt:
253.3
Formula:
C16H15NO2
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
175135-47-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Cheng et al (2015) Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers. J.Med.Chem. 58 4976. PMID: 25898186.

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Keywords: O4I1, supplier, induced, pluripotent, stem, cell, iPSCs, dedifferentiation, inducers, Oct3/4, reprogramming, Tocris Bioscience, Reprogramming products

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80 Stem Cell modulators supplied pre-dissolved in DMSO

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Written by K. Clarke et al

Stem Cells Scientific Review

Our Stem Cells review gives an overview of the use of small molecules in the control of stem cell growth & differentiation and somatic cell reprogramming. Request copy or view PDF today.

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