Cat. No. 5633
Chemical Name: 2-Thiouridine-5'-O-(α, β-methylene)diphosphate trisodium salt
Biological ActivityPotent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Lazarowski et al (2015) UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 88 151. PMID: 25829059.
Das et al (2010) Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 53 471. PMID: 19902968.
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Keywords: MRS 2905, supplier, MRS2905, Potent, selective, P2Y14, receptors, agonists, agonism, Tocris Bioscience, Purinergic (P2Y) Receptor Agonist products
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