MRS 2905

Cat. No. 5633

MRS 2905 C10H13N2Na3O10P2S

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Chemical Name: 2-Thiouridine-5'-O-(α, β-methylene)diphosphate trisodium salt

Biological Activity

Potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6.

Technical Data

Soluble to 45 mM in water
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Lazarowski et al (2015) UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 88 151. PMID: 25829059.

Das et al (2010) Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 53 471. PMID: 19902968.

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Keywords: MRS 2905, supplier, MRS2905, Potent, selective, P2Y14, receptors, agonists, agonism, Tocris Bioscience, Purinergic (P2Y) Receptor Agonist products

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