Cat. No. 5627
Chemical Name: Ethyl 2-amino-7-hydroxy-4-(3-pyridinyl)-4
Biological ActivityInsulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). Improves memory in control and memory-deficient mice models.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Albiston et al (2010) Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase. Mol.Pharmacol. 78 600. PMID: 20628006.
If you know of a relevant reference for HFI 142 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses HFI 142 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: HFI 142, supplier, HFI, 142, inhibitors, inhibits, insulin-regulated, aminopeptidases, IRAPs, memory, Tocris Bioscience, Aminopeptidase Inhibitor products