N-Acetylcysteine amide

Cat. No. 5619

N-Acetylcysteine amide C5H10N2O2S [38520-57-9]

Price and Availability

For N-Acetylcysteine amide pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (2R)-2-(Acetylamino)-3-mercaptopropanamide

Biological Activity

Glutathione (GSH) precursor and cell permeable antioxidant. Improves neuronal mitochondrial bioenergetics, reduces tissue damage and enhances functional recovery following spinal cord injury in rats. Also enhances behavioral recovery in rats following traumatic brain injury. Neuroprotective.

Technical Data

M.Wt:
162.21
Formula:
C5H10N2O2S
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Storage:
Store at -20°C
CAS No:
38520-57-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Pandya et al (2014) N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI. Exp.Neurol. 257 106. PMID: 24792639.

Patel et al (2014) N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma. Exp.Neurol. 257 95. PMID: 24805071.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for N-Acetylcysteine amide include:

Gutierrez et al (2014) The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. J Biol Chem 289 33568. PMID: 25301941.

Do you know of a great paper that uses N-Acetylcysteine amide from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: N-Acetylcysteine amide, supplier, cell, permeable, antioxidant, neuroprotective, glutathione, precursor, GSH, organoids, Tocris Bioscience, Antioxidant products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

New Product Guide (Fall/Winter 2016)

Our New Product guide highlights over 100 new products added in the second half of 2016. Request copy or view PDF today.

divider line

New Products in this Area

Filipin III

Polyene antibiotic; inhibits formation of pathological isoform of prion protein

Chaetoglobosin A

Antibiotic; selective apoptosis inducer of CLL cells

Sign-up for new product e-alerts
divider line

Bio-Techne Events

AACR 2017

AACR Annual Meeting 2017

April 1 - 5, 2017

Washington, D.C., USA

Booth: 1239