Cat. No. 5605
Chemical Name: Ethyl [5-[(diethylamino)acetyl]-10,11-dih
Biological ActivityPotent CAR antagonist (IC50 = 70 nM). Exhibits >90-fold selectivity for CAR over pregnane X receptor (PXR). Also selective over a panel of other nuclear receptors including FXR, LXR, PPARγ and RXR.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Cherian et al (2015) CINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptor. Mol.Pharmacol. 87 878. PMID: 25762023.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses CINPA 1 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: CINPA 1, supplier, CINPA1, CAR, constitutive, androstane, receptors, potent, antagonists, Tocris Bioscience, Constitutive Androstane Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
Synthetic retinoid; induces differentiation of stem cellsSI-2 hydrochloride
Steroid receptor coactivator 3 (SRC-3) inhibitorSR 0987
T cell-specific RORγ (RORγt) agonistWAY 252623
Potent LXR agonistSR 9009
December 3 - 7, 2016
San Francisco, CA,