Cat. No. 5599
Chemical Name: (αS)-N-[[1-(4-Methoxyphenyl)cyclohex
Biological ActivityBombesin receptor subtype 3 (BRS-3) antagonist (IC50 = 4.8 μM). Also binds GRPR (IC50 = 16 μM). Inhibits BA1-stimulated cytosolic Ca2+ and suppresses cell proliferation in a lung cancer model in vitro.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Moody et al (2015) ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides 64 55. PMID: 25554218.
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Keywords: ML 18, supplier, ML18, Bombesin, receptors, BRS, 3, PD168368, neuromedin, B, NMBR, gastrin, releasing, peptide, GRPR, lung, cancer, Tocris Bioscience, Bombesin Receptor Antagonist products
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