Cat. No. 5586
Chemical Name: 2-[5-[[(2,6-Dichlorophenyl)methyl]t
Biological ActivityPiezo1 channel activator. Slows the inactivation phase of transient currents, sensitizes Piezo1 to activation by pressure, and partially activates channels in the absence of external pressure, in HEK cells expressing Piezo1 channels.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Syeda et al (2015) Chemical activation of the mechanotransduction channel Piezo1. ELife 4 e07369. PMID: 26001275.
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Keywords: Yoda 1, supplier, Yoda1, Piezo1, calcium, channels, activators, sensitizers, sensitizes, Ca2+, currents, mechanotransduction, Tocris Bioscience, Other Calcium Channel Activator products
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