Cat. No. 1562
Alternative Names: [Ile5]Angiotensin I (1-7), Ang-(1-7)
Biological ActivityEndogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Santos et al (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc.Natl.Acad.Sci.U.S.A. 100 8258. PMID: 12829792.
Lemos et al (2002) Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats. Br.J.Pharmacol. 135 1743. PMID: 11934815.
Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45. PMID: 10967201.
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Keywords: Angiotensin (1-7), supplier, Vasorelaxant, peptide, AT, Receptors, Non-Selective, Angiotensin, agonists, Mas, Tocris Bioscience, Non-selective AT Receptor Agonist products
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September 27 - 30, 2017