Cat. No. 1562
Alternative Names: [Ile5]Angiotensin I (1-7), Ang-(1-7)
Biological ActivityEndogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Santos et al (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc.Natl.Acad.Sci.U.S.A. 100 8258. PMID: 12829792.
Lemos et al (2002) Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats. Br.J.Pharmacol. 135 1743. PMID: 11934815.
Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45. PMID: 10967201.
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Keywords: Angiotensin (1-7), supplier, Vasorelaxant, peptide, AT, Receptors, Non-Selective, Angiotensin, agonists, Mas, Tocris Bioscience, Non-selective AT Receptor Agonist products
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