Cat. No. 5549

Perlapine C19H21N3 [1977-11-3]

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Chemical Name: 6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepine

Biological Activity

Potent and selective hM3Dq DREADD agonist (EC50 = 2.8 nM). Exhibits >10,000-fold selectivity for hM3Dq over hM3.

Technical Data

Soluble to 50 mM in DMSO and to 5 mM in water with gentle warming
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Chen et al (2015) The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem.Neurosci. 6 476. PMID: 25587888.

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