Cat. No. 5521
Chemical Name: 3,4-Dihydro-N-(5-methyl-3-isoxazoly
Biological ActivitySelective TRPM3 agonist. Exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. Stimulates insulin release from pancreatic islet cells in vitro. Evokes nocifensive behavior in mice.
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Certificate of Analysis / Product Datasheet / Safety Datasheet
Held et al (2015) Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release. Proc.Natl.Acad.Sci.U.S.A. 112 E1363. PMID: 25733887.
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Keywords: CIM 0216, supplier, CIM0216, TRPM3, transient, potential, membrane, ion, channels, pain, insulin, Tocris Bioscience, TRPM Agonist products