Cat. No. 5521
Chemical Name: 3,4-Dihydro-N-(5-methyl-3-isoxazoly
Biological ActivitySelective TRPM3 agonist. Exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. Stimulates insulin release from pancreatic islet cells in vitro. Evokes nocifensive behavior in mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Held et al (2015) Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release. Proc.Natl.Acad.Sci.U.S.A. 112 E1363. PMID: 25733887.
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Keywords: CIM 0216, supplier, CIM0216, TRPM3, transient, potential, membrane, ion, channels, pain, insulin, Tocris Bioscience, TRPM Agonist products
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