Cat. No. 5495
Chemical Name: 4-Fluoro-N-[5-fluoro-6-(5-methoxypy
Biological ActivitycAMP/PKA/CREB pathway activator. Promotes osteogenic differentiation of human bone marrow-derived MSCs in vitro. Increases bone mass and bone volume density in ovariectomized mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Kim et al (2013) An activator of the cAMP/PKA/CREB pathway promotes osteogenesis from human mesenchymal stem cells. J.Cell.Physiol. 228 617. PMID: 22886506.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses CW 008 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: CW 008, supplier, CW008, MSC, mesenchymal, stem, cells, protein, kinase, A, PKA, activators, CREB, cAMP, osteogenic, osteogenesis, activators, activates, Tocris Bioscience, Protein Kinase A Activator products
Find multiple products by catalog number
New Products in this Area
Selective non-ATP competitive inhibitor of GSK 3βBI 605906
Selective IKKβ inhibitorGSK 319347A
Potent and selective IKKε inhibitorFRAX 597
Potent group I PAK inhibitorMRT 68921 dihydrochloride
Potent ULK inhibitor; inhibits autophagyAM 2394
Potent glucokinase activator; orally bioavailableeCF 309
Potent mTOR inhibitorPF 3758309 dihydrochloride
Potent PAK4 inhibitor; orally availableAZ Dyrk1B 33
Potent and selective Dyrk1B kinase inhibitorPF 06409577
Potent and selective allosteric activator of AMPKPerifosine
PKB/Akt inhibitor; also modulates Kv2.1 currentRAF 265
Raf kinase and VEGFR-2 inhibitorCZC 25146
Potent LRRK2 inhibitorRo 3280
Potent and selective PLK1 inhibitorRMM 46
MSK/RSK family kinase inhibitorLTURM 34
Potent DNA-PK inhibitorMLi-2
Potent and selective LRRK2 inhibitorLTURM 36
PI 3-kinase δ inhibitorPI 3065
Potent and selective PI 3-kinase p110δ inhibitorAZ PFKFB3 67
Potent and selective PFKFB3 inhibitorSTOCK2S 26016
Lysine deficient protein kinase (WNK) signaling inhibitor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.