Cat. No. 5488
Chemical Name: (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
Biological ActivityFPR2 (lipoxin A4 receptor) agonist. Suppresses tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. Also protects against hemorrhagic shock-induced acute lung injury in rats. Lipoxin A4 analog.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Gong et al (2012) BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats. Resuscitation. 83 907. PMID: 22245750.
Chen et al (2010) Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis. Mol.Cancer.Ther. 9 2164. PMID: 20682645.
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Keywords: BML 111, supplier, BML111, formyl, peptide, receptors, FPR2, agonists, agonism, lipoxinA4, LPA4, Tocris Bioscience, Formyl Peptide Receptor Agonist products
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