Cat. No. 5488
Chemical Name: (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
Biological ActivityFPR2 (lipoxin A4 receptor) agonist. Suppresses tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. Also protects against hemorrhagic shock-induced acute lung injury in rats. Lipoxin A4 analog.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Gong et al (2012) BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats. Resuscitation. 83 907. PMID: 22245750.
Chen et al (2010) Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis. Mol.Cancer.Ther. 9 2164. PMID: 20682645.
If you know of a relevant reference for BML 111 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses BML 111 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: BML 111, supplier, BML111, formyl, peptide, receptors, FPR2, agonists, agonism, lipoxinA4, LPA4, Tocris Bioscience, Formyl Peptide Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Reverse analog of BradykininTASP 0390325
Potent and selective V1B receptor antagonist; orally bioavailableML 233
Non-peptide apelin receptor agonistAmylin (rat)
Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptorsCalcitonin (human)
Endogenous calcitonin receptor agonist; inhibits bone resorptionSpexin
Potent GAL2/3 agonist; exhibits anxiolytic effects in vivoMM 54
Potent apelin receptor antagonist
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.