Cat. No. 5484
Chemical Name: 3-Phenyl-1-(4-phenyl-2-thiazolyl)-1
Biological ActivityTNF-α inhibitor (Kd = 110 nM for hTNF-α). Inhibits TNF-α-induced cytotoxicity in L929 fibroblast cells. Attenuates inflammation and increases survival in a mouse hepatitis model.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Ma et al (2014) A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse model. J.Biol.Chem. 289 12457. PMID: 24634219 .
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Keywords: C 87, supplier, TNF-alpha, TNF-a, TNF-α, tumor, necrosis, factor, inflammation, inhibitors, C87, 1609281-56-2, inhibits, Tocris Bioscience, Cytokine products
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