Cat. No. 5482
Biological ActivityProtein arginine deiminase 4 (PAD4) inhibitor (IC50 values are 2.3, 8.5, 26 and 71 μM for PAD4, PAD1, PAD3 and PAD2, respectively).
(Modifications: Thr-1 = N-terminal Ac, X = N5-(2-fluoro-1-iminoethyl)]-Or
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Jones et al (2012) Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem.Biol. 7 160. PMID: 22004374.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses TDFA from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: TDFA, supplier, PAD4, protein, arginine, deiminase, 4, inhibits, inhibitors, Tocris Bioscience, Post-Translational Modification Inhibitor products
Find multiple products by catalog number
New Products in this Area
High affinity caveolin-1 ligandSAG 21k
Hedgehog signaling activator; brain penetrant and orally bioavailableG10
Activator of STING-dependent signaling
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.