Cat. No. 1556
Alternative Name: 6'-IRTX
Chemical Name: [(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-
Biological ActivityHigh affinity TRPV1 (VR1) vanilloid receptor partial agonist (Ki = 0.71 nM; EC50 = 130 nM at human VR1). Displays partial agonism at human VR1 and full agonism at rat VR1.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
McDonnell et al (2002) Synthesis and in vitro evaluation of a novel iodinated resiniferatoxin derivative that is an agonist at the human vanilloid VR1 receptor. Bioorg.Med.Chem.Lett. 12 1189. PMID: 11934585.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses 6'-Iodoresiniferatoxin from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: 6'-Iodoresiniferatoxin, supplier, High, affinity, TRPV1, agonists, partial, Vanillioid, Receptors, VR1, TRPV, Channels, Transient, Receptor, Potential, 6-Iodoresiniferatoxin, 6-IRTX, Tocris Bioscience, TRPV Agonist products
Find multiple products by catalog number
New Products in this Area
Potent TRPV1 antagonistPF 05105679
Selective TRPM8 blockerM 084 hydrochloride
TRPC4/5 channel blocker; antidepressant and anxiolytic
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.