Cat. No. 5461
Biological ActivityWnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.
(Modifications: Met-1 = N-Formyl)
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Säfholm et al (2008) The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin.Cancer Res. 14 6556. PMID: 18927296.
Säfholm et al (2006) A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J.Biol.Chem. 281 2740. PMID: 16330545.
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Keywords: Foxy 5, supplier, Foxy5, wnt5a, peptide, mimetic, Tocris Bioscience, Other Wnt Signaling products
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