BRD 9876

Cat. No. 5454

BRD 9876 C16H14N2 [32703-82-5]

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Chemical Name: 6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile

Biological Activity

ATP non-competitive kinesin Eg5 inhibitor. Selectively inhibits microtubule-bound Eg5. Inhibits multiple myeloma cell growth (IC50 = 2.2 μM).

Technical Data

M.Wt:
234.3
Formula:
C16H14N2
Solubility:
Soluble to 50 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
32703-82-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Chattopadhyay et al (2015) Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors. Cell Rep. 10 755. PMID: 25660025.

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Keywords: BRD 9876, supplier, BRD9876, ATP, non-competitive, kinesin-5, Eg5, inhibitors, inhibits, microtubule-bound, Tocris Bioscience, Kinesin Inhibitor products

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