Cat. No. 5454
Chemical Name: 6-(1,1-Dimethylethyl)-2,3-naphthale
Biological ActivityATP non-competitive kinesin Eg5 inhibitor. Selectively inhibits microtubule-bound Eg5. Inhibits multiple myeloma cell growth (IC50 = 2.2 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Chattopadhyay et al (2015) Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors. Cell Rep. 10 755. PMID: 25660025.
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Keywords: BRD 9876, supplier, BRD9876, ATP, non-competitive, kinesin-5, Eg5, inhibitors, inhibits, microtubule-bound, Tocris Bioscience, Kinesin Inhibitor products