Cat. No. 5454
Chemical Name: 6-(1,1-Dimethylethyl)-2,3-naphthale
Biological ActivityATP non-competitive kinesin Eg5 inhibitor. Selectively inhibits microtubule-bound Eg5. Inhibits multiple myeloma cell growth (IC50 = 2.2 μM).
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Chattopadhyay et al (2015) Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors. Cell Rep. 10 755. PMID: 25660025.
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Keywords: BRD 9876, supplier, BRD9876, ATP, non-competitive, kinesin-5, Eg5, inhibitors, inhibits, microtubule-bound, Tocris Bioscience, Kinesin Inhibitor products