Cat. No. 5421
Chemical Name: 2-(4-Hydroxyphenyl)benzo[b]thiophen
Biological ActivitySelective estrogen receptor modulator (SERM); induces regression of tamoxifen-resistant, hormone independent xenograft tumors. Displays no significant gain in uterine weight in treated mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Molloy et al (2014) Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer. Mol.Cancer.Ther. 13 2515. PMID: 25205655.
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Keywords: BTC, supplier, oestrogen, receptors, modulators, SERM, tamoxifen, resistant, antitumor, antitumour, Tocris Bioscience, Estrogen and Related Receptor Modulator products
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