BTC

Cat. No. 5421

BTC C14H10O2S [63676-22-2]

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Chemical Name: 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol

Biological Activity

Selective estrogen receptor modulator (SERM); induces regression of tamoxifen-resistant, hormone independent xenograft tumors. Displays no significant gain in uterine weight in treated mice.

Technical Data

M.Wt:
242.29
Formula:
C14H10O2S
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in ethanol
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
63676-22-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Molloy et al (2014) Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer. Mol.Cancer.Ther. 13 2515. PMID: 25205655.

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Keywords: BTC, supplier, oestrogen, receptors, modulators, SERM, tamoxifen, resistant, antitumor, antitumour, Tocris Bioscience, Estrogen and Related Receptor Modulator products

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