Cat. No. 5420
Chemical Name: (3,5-Dibromo-4-hydroxyphenyl)(2-eth
Biological ActivityTMEM16A/B calcium-activated chloride channel (CaCC) blocker. Inhibits ATP-induced mucin secretion and metacholine-induced airway smooth muscle contraction in vitro.
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Certificate of Analysis / Product Datasheet / Safety Datasheet
Gallos et al (2013) Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle. Am.J.Physiol.Lung Cell Mol.Physiol. 305 625. PMID: 23997176.
Huang et al (2012) Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc.Natl.Acad.Sci.U.S.A. 109 16354. PMID: 22988107.
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Keywords: Benzbromarone, supplier, Benzbromarone, asthma, TMEM16A, TMEM16B, calcium, activated, chloride, channels, blockers, CACC, Tocris Bioscience, Calcium-activated Chloride Channel Blocker products
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