CYM 5520

Cat. No. 5418

CYM 5520 C21H19N3O2 [1449747-00-5]

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Chemical Name: 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile

Biological Activity

Selective S1P2 allosteric agonist (EC50 = 0.48 μM). Selective for S1P2 receptors over a panel of 29 other receptors and transporters.

Technical Data

M.Wt:
345.39
Formula:
C21H19N3O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
1449747-00-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Satsu et al (2013) A sphingosine 1-phosphate receptor 2 selective allosteric agonist. Bioorg.Med.Chem. 21 5373. PMID: 23849205.

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Keywords: CYM 5520, supplier, selective, allosteric, agonists, sphingosine-1-phosphate, receptor, 2, S1P2, S1PR2, agonism, CYM5520, Tocris Bioscience, Sphingosine-1-Phosphate Receptor Agonist products

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