Cat. No. 5402
Chemical Name: (3R,6S,9S,12E,16S)-9-(4-Aminobutyl)
Biological ActivityInsulin degrading enzyme (IDE) inhibitor (IC50 = 50 nM); regulates insulin, glucagon and amylin levels, and improves glucose tolerance in a diabetic mouse model.
Licensing InformationSold for research purpose under license from Harvard University
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Maianti et al (2014) Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature 511 94. PMID: 24847884.
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Keywords: 6bK, supplier, Insulin, degrading, enzymes, IDE, inhibitors, inhibits, glucagon, amylin, glucose, tolerance, diabetic, diabetes, Tocris Bioscience, Insulin and Insulin-like Receptor products
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