Cat. No. 5345
Chemical Name: N-[2-Chloro-5-(trifluoromethyl)phen
Biological ActivitySelective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). Exhibits 14-fold selectivity for LYPLA1 over LYPLA2. Also selective over a panel of ~30 other serine hydrolases.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Adibekian et al (2013) Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2). Probe Reports from the NIH Molecular Libraries Program. PMID: 24624465.
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Keywords: ML 348, supplier, ML348, selective, reversible, lysophospholipase, 1, lypla1, inhibitors, inhibits, Tocris Bioscience, Other Hydrolase Inhibitor products