BRD 7116

Cat. No. 5336

BRD 7116 C28H36N2O4S [329059-55-4]

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Chemical Name: N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]

Biological Activity

Inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM). Exhibits >100-fold selectivity for LSCs over normal hematopoietic stem cells.

Technical Data

Soluble to 100 mM in DMSO and to 20 mM in ethanol
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Hartwell et al (2013) Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat.Chem.Biol. 9 840. PMID: 24161946.

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Keywords: BRD 7116, supplier, BRD7116, leukemia, stem, cells, inhibitors, inhibits, LSCs, Tocris Bioscience, Cancer Stem Cell products

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