BRACO 19 trihydrochloride
Cat. No. 5312
Chemical Name: N,N'-[9[[4-(Dimethylamino)phenyl]ami
Biological ActivityTelomerase inhibitor (IC50 = 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. Inhibits growth of uterine tumor xenografts in mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Burger et al (2005) The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function. Cancer Res. 15 1489. PMID: 15735037.
Gowan et al (2002) A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity. Mol.Pharmacol. 61 1154. PMID: 11961134.
If you know of a relevant reference for BRACO 19 trihydrochloride please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses BRACO 19 trihydrochloride from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: BRACO 19 trihydrochloride, supplier, BRACO19, trihydrochloride, telomerase, inhibitor, inhibits, Tocris Bioscience, Telomerase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Potent PARP inhibitor; orally bioavailableEntecavir
Potent and selective hepatitis B virus inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.