Cat. No. 5293
Chemical Name: N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-
Biological ActivityNrf2 activator; interacts with the Nrf2-binding site of Keap1. Downregulates the expression of fibrogenic genes and increases antioxidant effects in NASH rat models of liver disease.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Shimozono et al (2013) Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol.Pharmacol. 84 62. PMID: 23592516.
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Keywords: NK 252, supplier, NK252, NRF2, activators, activates, Keap1, Tocris Bioscience, Nrf2 Activator products
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