AH 7614

Cat. No. 5256

AH 7614 C20H17NO3S [6326-06-3]

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Chemical Name: 4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide

Biological Activity

Selective free fatty acid receptor 4 (FFA4/GPR120) antagonist (pIC50 values are 7.1 and <4.6 for human FFA4 and FFA1 receptors respectively). Inhibits linoleic acid and GSK 137647A-induced intracellular calcium accumulation in U2OS osteosarcoma cells expressing the FFA4 receptor.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Technical Data

Soluble to 100 mM in DMSO
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Sparks et al (2014) Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). Bioorg.Med.Chem.Lett. 24 3100. PMID: 24881566.

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Keywords: AH 7614, supplier, AH7614, selective, free, fatty, acid, 4, FFA4, receptor, antagonist, GPR120, Tocris Bioscience, Free Fatty Acid Receptor Antagonist products

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