Cat. No. 5238
Chemical Name: (4S,5S,7E,9R,11Z,13S,15S,17S,19R,21
Biological ActivityPotent protein kinase C activator (KI = 2.75 nM). Attenuates phorbol 12-myristate 13-acetate (Cat. No. 1201) inhibition of GH4C1 pituitary cell proliferation in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Mackanos et al (1991) Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation. J.Biol.Chem. 266 1120. PMID: 1904062.
Wender et al (1988) Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C. Proc.Natl.Acad.Sci.U.S.A. 85 7197. PMID: 3174627.
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Citations are publications that use Tocris products.
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Keywords: Bryostatin 3, supplier, potent, protein, kinases, c, activator, Bryostatin, 3, natural, Tocris Bioscience, Protein Kinase C Activator products
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