Monensin sodium salt
Cat. No. 5223
Chemical Name: 2-[5-Ethyltetrahydro-5-[tetrahydro-
Biological ActivitySodium ionophore. Neutralizes acidic intracellular compartments. Disrupts Golgi apparatus structure and inhibits vesicular transport in eukaryotic cells. Induces apoptosis in prostate cancer cells. Antiprotozoal, antibacterial and antifungal agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Łowicki and Huczyński (2013) Structure and antimicrobial properties of monensin A and its derivatives: summary of the achievements. Biomed.Res.Int 2013. PMID: 23509771.
Ketola et al (2010) Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells. Mol.Cancer Ther. 9 3175. PMID: 21159605.
Mollenhauer et al (1990) Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity. Biochim.Biophys.Acta 1031 225. PMID: 2160275.
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Keywords: Monensin sodium salt, supplier, ionophores, ion, channels, modulators, antibacterial, antiprotozoal, antifungal, induces, apoptosis, Tocris Bioscience, Ionophore products