Cat. No. 5211
Chemical Name: (5Z)-5-[[(4-[(2-Methylphenyl)thio]-
Biological ActivityDNA polymerase λ and β inhibitor (IC50 values are 3.9 and 18.2 μM, respectively). Sensitizes human colorectal cancer cells to hydrogen peroxide and temozolomide (Cat. No. 2706) in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Strittmatter et al (2014) Expanding the scope of human DNA polymerase λ and β inhibitors. ACS Chem.Biol. 9 282. PMID: 24171552.
If you know of a relevant reference for AM-TS23 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses AM-TS23 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: AM-TS23, supplier, DNA, polymerases, inhibitors, lambda, beta, cancer, sensitizers, AM-TS23, β, λ, inhibits, Tocris Bioscience, RNA/DNA Polymerase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Potent PARP inhibitor; orally bioavailableEntecavir
Potent and selective hepatitis B virus inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.