Cat. No. 5211
Chemical Name: (5Z)-5-[[(4-[(2-Methylphenyl)thio]-
Biological ActivityDNA polymerase λ and β inhibitor (IC50 values are 3.9 and 18.2 μM, respectively). Sensitizes human colorectal cancer cells to hydrogen peroxide and temozolomide (Cat. No. 2706) in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Strittmatter et al (2014) Expanding the scope of human DNA polymerase λ and β inhibitors. ACS Chem.Biol. 9 282. PMID: 24171552.
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Keywords: AM-TS23, supplier, DNA, polymerases, inhibitors, lambda, beta, cancer, sensitizers, AM-TS23, β, λ, inhibits, Tocris Bioscience, RNA/DNA Polymerase Inhibitor products
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