Cat. No. 5209
Chemical Name: 4-[4-(3,4-Difluorophenyl)-2-pyrimid
Biological ActivityPotent FAAH inhibitor; (IC50 values are 0.28 and 0.72 nM, at rat and human FAAH respectively). Displays analgesic effects in vivo models of neuropathic and inflammatory pain. Brain penetrant.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kono et al (2014) Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. Bioorg.Med.Chem. 22 1468. PMID: 24440478.
If you know of a relevant reference for TAK 21d please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses TAK 21d from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: TAK 21d, supplier, TAK21d, potent, inhibitors, inhibits, fatty, acid, amide, hydrolase, FAAH, neuropathic, inflammatory, pain, analgesic, Tocris Bioscience, Fatty Acid Amide Hydrolase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Potent DDHD2 inhibitorPDD 00017273
Potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor; cell permeable
August 20 - 24, 2017
Paris , France