Cat. No. 5209
Chemical Name: 4-[4-(3,4-Difluorophenyl)-2-pyrimid
Biological ActivityPotent FAAH inhibitor; (IC50 values are 0.28 and 0.72 nM, at rat and human FAAH respectively). Displays analgesic effects in vivo models of neuropathic and inflammatory pain. Brain penetrant.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Kono et al (2014) Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. Bioorg.Med.Chem. 22 1468. PMID: 24440478.
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Keywords: TAK 21d, supplier, TAK21d, potent, inhibitors, inhibits, fatty, acid, amide, hydrolase, FAAH, neuropathic, inflammatory, pain, analgesic, Tocris Bioscience, Fatty Acid Amide Hydrolase Inhibitor products
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