Cat. No. 5193
Chemical Name: 4-[2-(2-Cyclopentylidenehydrazinyl)
Biological ActivityN-acetyltransferase 10 (NAT10) inhibitor. Improves nuclear shape in HGPS (Hutchinson-Gilford progeria syndrome) cells and lamin A/C depleted cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Larrieu et al (2014) Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science 344 527. PMID: 24786082.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Remodelin from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Remodelin, supplier, NAT10, N-acetyltransferase, 10, aging, inhibitors, HGPS, Hutchinson-Gilford, progeria, syndrome, laminopathies, laminopathy, inhibits, Tocris Bioscience, Other Transferase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Potent cholesteryl ester transfer protein (CETP) inhibitorPerhexiline maleate
Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitorMS 023 dihydrochloride
Potent and selective type I PRMT inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.