(R)-(+)-Bay K 8644
Cat. No. 1545
Chemical Name: (4R)-1,4-Dihydro-2,6-dimethyl-5-nit
Biological ActivityL-type Ca2+-channel blocker with negative inotropic and vasodilatatory effects in vivo. Enantiomer showing opposite effects to the racemate (±)-Bay K 8644 (Cat. No. 1544) and (S)-(-)- enantiomer (Cat. No. 1546).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Shi et al (2008) Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell. 3 568. PMID: 18983970.
Ravens and Schopper (1990) Opposite cardiac actions of the enantiomers of Bay K 8644 at different membrane potentials in guinea-pig papillary muscles. Naunyn Schmiedebergs Arch.Pharmacol. 341 232. PMID: 1692975.
O'Neill and Bolger (1988) Enantiomer selectivity and the development of tolerance to the behavioral effects of the calcium channel activator BAY K 8644. Brain Res.Bull. 21 865. PMID: 2465070.
Franckowiak et al (1985) The optical isomers of the 1,4-dihydropyridine BAY K 8644 show opposite effects on Ca channels. Eur.J.Pharmacol. 114 223. PMID: 2412855.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses (R)-(+)-Bay K 8644 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: (R)-(+)-Bay K 8644, supplier, Ca2+-channel, blockers, L-type, Calcium, CaV, Channels, L-Type, voltage-gated, voltage-dependent, Ca2+, (R)-(+)-BayK8644, stem, cells, Tocris Bioscience, Voltage-gated Calcium Channel (CaV) Blocker products
Find multiple products by catalog number
March 18 - 22, 2017
Little Rock, ARK, USA