Cat. No. 5175
Chemical Name: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
Biological ActivityBroad spectrum, irreversible inhibitor of serine proteases. Also inhibits NADPH oxidase activation in vitro. Attenuates airway inflammation in a mouse model of airway allergy.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Saw et al (2012) Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease. PLoS ONE 7 e41107. PMID: 22829914.
Diatchuk et al (1997) Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds. J.Biol.Chem. 272 13292. PMID: 9148950.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses AEBSF from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: AEBSF, supplier, broad, spectrum, irreversible, serine, proteases, inhibitors, inhibits, trypsin, chymotrypsin, plasmin, thrombin, kallikreins, Tocris Bioscience, Other Protease Inhibitor products
Find multiple products by catalog number
New Products in this Area
Selective high affinity MMP2 inhibitor(R)-MG 132
Potent 20S proteasome inhibitorDiprotin A
Dipeptidyl peptidase IV (DPP-IV) inhibitor
April 22 - 26, 2017
Chicago, IL, USA