Cat. No. 5175

AEBSF C8H10FNO2S.HCl [30827-99-7]

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Chemical Name: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride

Biological Activity

Broad spectrum, irreversible inhibitor of serine proteases. Also inhibits NADPH oxidase activation in vitro. Attenuates airway inflammation in a mouse model of airway allergy.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Saw et al (2012) Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease. PLoS ONE 7 e41107. PMID: 22829914.

Diatchuk et al (1997) Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds. J.Biol.Chem. 272 13292. PMID: 9148950.

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Keywords: AEBSF, supplier, broad, spectrum, irreversible, serine, proteases, inhibitors, inhibits, trypsin, chymotrypsin, plasmin, thrombin, kallikreins, Tocris Bioscience, Other Protease Inhibitor products

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