Cat. No. 5169
Alternative Name: Norepinephrine
Chemical Name: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2
Biological ActivityEndogenous adrenergic hormone and neurotransmitter. A classical stress hormone; underlies the fight or flight response, along with adrenaline. Increases heart rate. Vasoconstrictor.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Lewitt et al (2012) Norepinephrine: the next therapeutics frontier for Parkinson's disease. Transl.Neurodegener. 1 4. PMID: 23211006.
Gary et al (1985) Stress and brain noradrenaline: A review. Neuroscience & Biobehavioral Reviews 9 233.
Bunney et al (1965) Norepinephrine in depressive reactions. A review. Arch.Gen.Psychiatry. 13 483. PMID: 5320621.
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Citations are publications that use Tocris products. Selected citations for Noradrenaline bitartrate include:
Baj et al (2012) Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacology 37 1600. PMID: 22318196.
Zemkova et al (2011) Norepinephrine causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+. Endocrinology 152 3842. PMID: 21828176.
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Keywords: Noradrenaline bitartrate, supplier, endogenous, adrenergic, hormones, neurotransmitters, vasoconstrictor, stress, Tocris Bioscience, Non-selective Adrenergic α Receptor Agonist products
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Selective, high affinity, non-competitive α1A adrenoceptor antagonist
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