Perhexiline maleate

Cat. No. 5166new

Perhexiline maleate C19H35N.C4H4O4 [6724-53-4]

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Chemical Name: 2-(2,2-Dicyclohexylethyl)piperidine maleate

Biological Activity

Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor. Inhibits palmitate oxidation in rat cardiomyocytes and increases cardiac efficiency in isolated rat hearts. Antianginal.

Technical Data

M.Wt:
393.56
Formula:
C19H35N.C4H4O4
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
6724-53-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Yin et al (2013) Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome. J.Mol.Cell.Cardiol. 55 27. PMID: 23277191.

Unger et al (2005) Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium. J.Cardiovasc.Pharmacol. 46 849. PMID: 16306812.

Kennedy et al (1996) Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone. Biochem.Pharmacol. 52 273. PMID: 8694852.

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Keywords: Perhexiline maleate, supplier, Carnitine, palmitoyltransferase-1/2, CPT1, CPT2, antianginal, cardiac, inhibits, inhibitors, Tocris Bioscience, Other Transferase Inhibitor products

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