Cat. No. 1659
Alternative Name: SKF 82526
Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-(4-hy
Biological ActivitySelective D1-like dopamine receptor partial agonist (EC50 = 57 nM). Vasodilator in vivo and does not readily cross the blood-brain barrier. Also α2-adrenoceptor antagonist in vitro (Ki = 15 - 25 nM).
Licensing InformationSold for research purposes under agreement from GlaxoSmithKline
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Nichols et al (1990) The pharmacology of fenoldopam. Am.J.Hypertens. 3 116S. PMID: 1974439.
Hahn et al (1982) Characterization of the peripheral and central effects of SK&F 82526, a novel dopamine receptor agonist. J.Pharmacol.Exp.Ther. 223 305. PMID: 6127401.
Sibley et al (1982) Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors. Life Sci. 31 637. PMID: 6127585.
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Citations are publications that use Tocris products. Selected citations for Fenoldopam hydrochloride include:
Chen et al (2013) Gastrin and D1 dopamine receptor interact to induce natriuresis and diuresis. Hypertension 62 927. PMID: 24019399.
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Keywords: Fenoldopam hydrochloride, supplier, Selective, D1-like, partial, agonists, Dopamine, Receptors, D5, dopaminergic, SKF82526, GlaxoSmithKline, GSK, Tocris Bioscience, D1 and D5 Receptor Agonist products