Fenoldopam hydrochloride

Cat. No. 1659

Fenoldopam hydrochloride C16H16ClNO3.HCl [181217-39-0]

Price and Availability

For Fenoldopam hydrochloride pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Name: SKF 82526

Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol hydrochloride

Biological Activity

Selective D1-like dopamine receptor partial agonist (EC50 = 57 nM). Vasodilator in vivo and does not readily cross the blood-brain barrier. Also α2-adrenoceptor antagonist in vitro (Ki = 15 - 25 nM).

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Technical Data

Soluble to 10 mM in water
>98 %
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Nichols et al (1990) The pharmacology of fenoldopam. Am.J.Hypertens. 3 116S. PMID: 1974439.

Hahn et al (1982) Characterization of the peripheral and central effects of SK&F 82526, a novel dopamine receptor agonist. J.Pharmacol.Exp.Ther. 223 305. PMID: 6127401.

Sibley et al (1982) Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors. Life Sci. 31 637. PMID: 6127585.

If you know of a relevant reference for Fenoldopam hydrochloride please let us know.

Citations are publications that use Tocris products. Selected citations for Fenoldopam hydrochloride include:

Chen et al (2013) Gastrin and D1 dopamine receptor interact to induce natriuresis and diuresis. Hypertension 62 927. PMID: 24019399.

Do you know of a great paper that uses Fenoldopam hydrochloride from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Fenoldopam hydrochloride, supplier, Selective, D1-like, partial, agonists, Dopamine, Receptors, D5, dopaminergic, SKF82526, GlaxoSmithKline, GSK, Tocris Bioscience, D1 and D5 Receptor Agonist products

Quick Order

Find multiple products by catalog number

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Product Guide

Our Neurodegeneration guide highlights over 275 products for neurodegeneration research. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

Dopamine Scientific Review

Written by P. Strange & K.Neve

Dopamine Receptors Scientific Review

Our Dopamine receptors review gives an overview of the dopamine receptor subtypes, and the receptor agonists and antagonists used to study them. Request copy or view PDF today.

divider line

Cardiovascular Life Science Poster

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Life Science Poster

Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity. Request copy or view PDF today.

divider line

Depression Life Science Poster

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

divider line

Parkinson's Life Science Poster

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

divider line

Addiction Life Science Poster

Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

divider line

New Products in this Area

MLS 1547

G protein-biased D2 receptor partial agonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

26th ISN-ESN Biennal Meeting

26th ISN-ESN Biennial Meeting

August 20 - 24, 2017

Paris , France

Booth: 11